Product Description of Sesamol CAS#533-31-3
Named alternatively as 3,4-methylenedioxyphenol, sesamol is one kind of lipid-soluble lignan and a vital natural component extracted from sesame oil. This ingredient keeps sesame-oil quality and chemical stability well-protected. It exists naturally inside sesame kernels, crude sesame oil and sesame seed residue. The compound is produced on an ongoing basis when sesamolin undergoes thermal breakdown during manufacturing procedures, reaching a maximum content of 64.4 milligrams within every 100-gram portion of sesame oil.
Sesamol is a white to off‑white crystalline powder with a characteristic mild phenolic odor, having a molecular formula of C₇H₆O₃ and a molecular weight of 138.12. The product has a melting point of approximately 62–65 °C and dissolves readily in ethanol, ether and most organic solvents, while showing only limited solubility in water. Owing to its phenolic hydroxyl group, sesamol exhibits notable antioxidant activity and is also widely used as a versatile intermediate in the synthesis of fine chemicals, pharmaceutical molecules and cosmetic ingredients. The compound is sensitive to light and air and tends to discolor upon prolonged exposure, so it should be stored in a tightly sealed, dark and cool environment to maintain its purity and appearance during handling and transport.
Sesamol Chemical Properties
| Melting point | 62-65 °C (lit.) |
| Boiling point | 113-116°C 2mm |
| density | 1.2112 (rough estimate) |
| refractive index | 1.4850 (estimate) |
| Fp | 113-116°C/2mm |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Chloroform, Methanol |
| form | Crystalline powder |
| pka | 10.08±0.20(Predicted) |
| color | White to off‑white |
| Water Solubility | slightly soluble |
| Sensitive | Light Sensitive |
| BRN | 127405 |
| InChIKey | LUSZGTFNYDARNI-UHFFFAOYSA-N |
| LogP | 1.253 (est) |
| CAS DataBase Reference | 533-31-3(CAS DataBase Reference) |
| NIST Chemistry Reference | 1,3-Benzodioxol-5-ol(533-31-3) |
| EPA Substance Registry System | Sesamol (533-31-3) |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| RTECS | SM0890000 |
| Hazard Note | Irritant |
| TSCA | Yes |
| HS Code | 29329970 |
| Hazardous Substances Data | 533-31-3(Hazardous Substances Data) |
Product Application of Sesamol CAS#533-31-3
Natural sesame-oil contains sesamol with a comparatively low content. Being an aromatic phenolic substance, it is capable of carrying out chemical reactions with acids, aldehydes, alcohols and phenolic materials to yield diverse ether and ester derivatives.
This natural compound is utilised extensively for manufacturing fine-chemical products. The covered categories comprise antibacterial-antifungal reagents, anti-tumour and hypotensive pharmaceuticals, as well as functional additives for high-end shampoo. Regarded as a premium-grade synthetic precursor for pharmacy, it possesses great research value and promising market prospects.
Apart from the above-mentioned fields, sesamol works as a key building-block when creating cerebrovascular-treatment medicines, blood-pressure-reducing preparations, anti-cancer raw materials and synergistic additives for farm-use pesticides.
